In vitro susceptibility of Mycobacterium tuberculosis clinical isolates to garenoxacin and DA-7867.

نویسندگان

  • Lucio Vera-Cabrera
  • Jorge Castro-Garza
  • Adrian Rendon
  • Jorge Ocampo-Candiani
  • Oliverio Welsh
  • Sung Hak Choi
  • Kym Blackwood
  • Carmen Molina-Torres
چکیده

The in vitro activities of DA-7867, a novel oxazolidinone, and garenoxacin (BMS-284756) were compared to those of linezolid in 67 susceptible and drug-resistant clinical isolates of Mycobacterium tuberculosis. DA-7867 was the most active drug with an MIC(90) of 0.125 microg/ml, compared to the MIC(90)s of 4 microg/ml of garenoxacin and 2 microg/ml of linezolid.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 49 10  شماره 

صفحات  -

تاریخ انتشار 2005